Built outside the walls, next to the castle and to one of the city's Roman outposts, the Évora gate, this church in the simplicity of its façade “hides” the artistic-architectural preciousness that it keeps inside. A remarkable set of capitals attest to its Visigothic origin.

In the 14th century, it underwent some alterations related to the mortal remains of João Mendes, D. Dinis' squire. Its current façade dates back to the 17th century, in which one of the “Steps” of the Via Sacra was added,

In the 19th century, tile panels depicting hunting scenes, authored by the famous painter Gabriel del Barco, were torn out of its interior.

Until the end of the 19th century, on January 15th, this church held a curious feast in honor of Santo Amaro, in which cakes and sweets in the shape of arms and legs were sold and auctioned. It was believed that whoever ate these cakes would be free from suffering in the members during the year, as Santo André is considered the protector of the crippled.

The Visigothic Nucleus of the Museu Regional de Beja is currently installed here.